Mercedes-Benz E450 4matic
2019–2026 · 8 configurations
The Mercedes-Benz E450 4matic has been tested by the EPA across 8 different configurations spanning model years 2019 through 2026. Over this period, the E450 4matic has achieved combined fuel economy ratings ranging from 23 MPG to 26 MPG, with an overall average of 25 MPG across all engine, transmission, and drivetrain combinations. Below you will find a comprehensive breakdown of every tested configuration, organized by model year. Click any row to view detailed specifications, emissions data, and annual fuel cost estimates for that specific vehicle.
All Configurations
| Year | Powertrain | Annual Cost | City | Hwy | Comb MPG | Compare |
|---|---|---|---|---|---|---|
| 2026 | 3L 6-cyl All-Wheel Drive Automatic 9-spd • Premium | $2,750 | 22 | 31 | 25MPG | |
| 2025 | 3L 6-cyl All-Wheel Drive Automatic 9-spd • Premium | $2,750 | 22 | 31 | 25MPG | |
| 2024 | 3L 6-cyl All-Wheel Drive Automatic 9-spd • Premium | $2,750 | 22 | 31 | 25MPG | |
| 2023 | 3L 6-cyl All-Wheel Drive Automatic 9-spd • Premium | $2,650 | 23 | 31 | 26MPG | |
| 2022 | 3L 6-cyl 4-Wheel Drive Automatic 9-spd • Premium | $2,750 | 23 | 30 | 25MPG | |
| 2021 | 3L 6-cyl 4-Wheel Drive Automatic 9-spd • Premium | $2,650 | 23 | 30 | 26MPG | |
| 2020 | 3L 6-cyl 4-Wheel Drive Automatic 9-spd • Premium | $3,000 | 20 | 28 | 23MPG | |
| 2019 | 3L 6-cyl 4-Wheel Drive Automatic 9-spd • Premium | $3,000 | 20 | 28 | 23MPG |
Historical Efficiency
Safety Rating History
NHTSA typically tests the base platform of a vehicle and does not test every specific trim level. This specific configuration (E450 4matic) has not been independently rated.
Complaint & Incident History
The data below represents all official consumer complaints reported to the National Highway Traffic Safety Administration (NHTSA) for the Mercedes-Benz E450 4matic. Click on any year to drill down and read the unedited, raw problem narratives submitted directly by vehicle owners.
No NHTSA consumer complaints have been reported for this model.