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2006Standard Pickup Trucks 4WDRegular

2006 Isuzu i-350 Crew Cab 4WD

EPA ID: 22282
16
City MPG
17
Combined MPG
17MPG· Below Avg
21
Highway MPG

Fuel Economy Overview

The 2006 Isuzu i-350 Crew Cab 4WD achieves an EPA-estimated 17 MPG in combined city and highway driving, with 16 MPG in the city and 21 MPG on the highway. Powered by a 3.5L 5-cylinder engine paired with a automatic 4-spd, this standard pickup trucks 4wd features 4-Wheel or All-Wheel Drive drive.

In terms of environmental impact, the 2006 i-350 Crew Cab 4WD produces approximately 523 grams of CO2 per mile. This figure is measured under standardized EPA test conditions and represents tailpipe emissions only. For context, the average new vehicle sold in the United States produces approximately 400 grams of CO2 per mile, meaning this i-350 Crew Cab 4WD has higher-than-average emissions in this regard.

The estimated annual fuel cost for this vehicle is $3,500, based on 15,000 miles of driving per year and current national average fuel prices. Compared to the average new vehicle, you would save $6,750 over a 5-year period. This calculation accounts for differences in fuel consumption efficiency and provides a practical measure of long-term ownership costs attributable to fuel economy.

Energy DNA

Vehicle ClassStandard Pickup Trucks 4WD
Fuel TypeRegular
Engine3.5L 5-cyl
AspirationNaturally Aspirated
TransmissionAutomatic 4-spd
Drive Type4-Wheel or All-Wheel Drive

Green Scorecard

CO2 Emissions523 g/mi
Start-Stop SystemNot Equipped
GHG Score-1/10
Smog RatingN/A
Est. Annual Cost$3,500
5-Year Cost DeltaSave $6,750

Personalized Commute CalculatorEPA defaults to 55% City / 45% Hwy

55% City45% Highway

Adjust the slider to match your daily driving habits. City driving involves stop-and-go traffic under 45mph, while highway driving represents sustained speeds over 55mph.

Your Real MPG
17.9
Impact vs EPA
$-159
/ year
💨

The Brick Effect: Highway Speed Penalty

EPA highway tests average roughly 48 mph. Driving at 75 mph increases aerodynamic drag exponentially. Because the Standard Pickup Trucks 4WD has a large frontal area, expect your real-world highway fuel economy to drop by up to 25% at high speeds.

5-Year Total Cost of Ownership

Estimated Monthly Cost
$734/mo
Includes estimated depreciation, fuel, insurance, and state fees over 5 years. Does not include loan interest.
15,000 mi
Value Depreciation
Est. value lost over 60 months
$16,800
38.1%
Fuel & Electricity
Based on National Average rates ($3.50/gal)
$15,441
35.1%
Estimated Insurance
Based on vehicle class risk profile
$11,400
25.9%
State Registration Fees
Based on National Average DMV base rates
$400
0.9%
Total 5-Year Cost$44,041

Recall Intelligence

Campaign #09V310000·2010-08-02
critical
Component: EXTERIOR LIGHTING:BRAKE LIGHTS:SWITCH

GM IS RECALLING 185,903 MODEL YEAR 2004-2009 COLORADO, GMC MODEL YEAR 2009-2004 CANYON, MODEL YEAR 2006 I-280, I-350, MODEL YEAR 2007-2008 I-290, AND I-370, PASSENGER VEHICLES ORIGINALLY SOLD IN OR CURRENTLY REGISTERED IN THE STATES OF ALABAMA, ARIZONA, FLORIDA, GEORGIA, HAWAII, LOUISIANA, MISSISSIPPI, NEVADA, NEW MEXICO, PUERTO RICO, SOUTH CAROLINA, TEXAS, U.S. VIRGIN ISLANDS AND UTAH. SOME OF THESE VEHICLES HAVE A BRAKE LAMP SWITCH THAT MAY NOT WORK AS DESIGNED DUE TO CONTAMINATION IN THE SWITCH.

Consequence & Remedy

Consequence: THIS CONDITION COULD CAUSE THE SIMULTANEOUS LOSS OF ALL BRAKE LAMPS OR CAUSE ALL OF THE BRAKE LAMPS TO STAY ON CONTINUOUSLY. BOTH OF THESE CONDITIONS COULD FAIL TO WARN OTHERS OF THE DRIVER'S INTENTIONS AND COULD LEAD TO A VEHICLE CRASH.

Remedy: DEALERS WILL INSPECT AND REPLACE THE NECESSARY COMPONENTS AS SPECIFIED IN THE RECALL BULLETIN FREE OF CHARGE. GM ANTICIPATES THAT PARTS WILL BE AVAILABLE BY JUNE 2010. A SPECIAL COVERAGE FOR VEHICLES REGISTERED IN ALL OTHER STATES WILL BE IMPLEMENTED IN THE SAME TIME FRAME. IN THE INTERIM, OWNERS WHO EXPERIENCE THE FAILURE CAN OBTAIN A FREE REPAIR, HOWEVER THEY WILL BE REQUIRED TO RETURN WHEN THE NEW DESIGN PART BECOMES AVAILABLE. OWNERS MAY CONTACT CHEVROLET AT 1-800-630-2438, GMC AT 1-866-996-9463, ISUZU AT 1-800-255-6727 OR AT WWW.GMOWNERCENTER.COM.

Campaign #06V139000·2006-12-05
critical
Component: EXTERIOR LIGHTING:BRAKE LIGHTS:SWITCH

CERTAIN PICKUP TRUCKS MAY EXPERIENCE THE PERMANENT LOSS OF BRAKE LAMP FUNCTION OR BRAKE LAMPS THAT ARE ILLUMINATED AT ALL TIMES. THE CENTER HIGH-MOUNTED STOP LAMP (CHMSL) IS AFFECTED IN BOTH INSTANCES. ALSO, IF EQUIPPED, THE CRUISE CONTROL WILL BECOME INOPERATIVE. ANY TRAILER BRAKE LAMPS WHICH ARE CONNECTED TO THE VEHICLE'S BRAKE LAMP WIRING WILL MIMIC THE VEHICLE'S BRAKE LAMPS WHEN EITHER CONDITION OCCURS.

Consequence & Remedy

Consequence: A FOLLOWING DRIVER MAY NOT KNOW WHEN THE BRAKES HAVE BEEN APPLIED, AND A REAR-END CRASH COULD OCCUR WITHOUT PRIOR WARNING.

Remedy: DEALERS WILL REPLACE THE BRAKE LAMP SWITCH ASSEMBLY. THE RECALL BEGAN ON DECEMBER 5, 2006. OWNERS MAY CONTACT CHEVROLET AT 1-800-630-2438; GMC AT 1-866-996-9463 OR ISUZU AT 1-800-255-6727.

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Looking for comprehensive historical data?

NHTSA FARS (Fatal Crash History) and broader generational safety trends are aggregated at the model level rather than by specific engine configurations. View the complete historical data profile for all Isuzu i-350 Crew Cab 4WD configurations.

View Model History

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Fuel Cost Analysis

Annual Fuel Cost$3,500
vs. Avg Vehicle (5 yrs)Save $6,750

Based on 15,000 miles/year and current fuel prices.

Efficiency Breakdown

City16 MPG
Highway21 MPG
Combined17 MPG

Estimated Lifetime Carbon Footprint

(Based on 200,000 miles driven)

104.6 metric tons CO₂
Equivalent To:
🌳 129 tree seedlings grown for 10 yrs
✈️ 8.7 cross-country flights/yr

Data Provenance

Data directly from the EPA National Vehicle and Fuel Emissions Laboratory. The combined rating is a weighted average (55% city, 45% highway). For official figures, visit fueleconomy.gov.