Do Not Drive — Critical Safety Warning

The NHTSA has issued a "Park It" advisory for this specific vehicle configuration. There is a catastrophic safety defect that poses an immediate risk of death or severe injury. Scroll down to the Recall Intelligence section for specific remedy instructions.

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2010Sport Utility Vehicle - 4WDPremium

2010 Mercedes-Benz ML350 4matic

EPA ID: 29375
15
City MPG
17
Combined MPG
17MPG· Below Avg
20
Highway MPG

Fuel Economy Overview

The 2010 Mercedes-Benz ML350 4matic achieves an EPA-estimated 17 MPG in combined city and highway driving, with 15 MPG in the city and 20 MPG on the highway. Powered by a 3.5L 6-cylinder engine paired with a automatic 7-spd, this sport utility vehicle - 4wd features 4-Wheel Drive drive.

In terms of environmental impact, the 2010 ML350 4matic produces approximately 523 grams of CO2 per mile. This figure is measured under standardized EPA test conditions and represents tailpipe emissions only. For context, the average new vehicle sold in the United States produces approximately 400 grams of CO2 per mile, meaning this ML350 4matic has higher-than-average emissions in this regard.

The estimated annual fuel cost for this vehicle is $4,050, based on 15,000 miles of driving per year and current national average fuel prices. Compared to the average new vehicle, you would save $9,500 over a 5-year period. This calculation accounts for differences in fuel consumption efficiency and provides a practical measure of long-term ownership costs attributable to fuel economy.

Energy DNA

Vehicle ClassSport Utility Vehicle - 4WD
Fuel TypePremium
Engine3.5L 6-cyl
AspirationNaturally Aspirated
TransmissionAutomatic 7-spd
Drive Type4-Wheel Drive

Green Scorecard

CO2 Emissions523 g/mi
Start-Stop SystemNot Equipped
GHG Score-1/10
Smog RatingN/A
Est. Annual Cost$4,050
5-Year Cost DeltaSave $9,500

Personalized Commute CalculatorEPA defaults to 55% City / 45% Hwy

55% City45% Highway

Adjust the slider to match your daily driving habits. City driving involves stop-and-go traffic under 45mph, while highway driving represents sustained speeds over 55mph.

Your Real MPG
16.9
Impact vs EPA
+$18
/ year
💨

The Brick Effect: Highway Speed Penalty

EPA highway tests average roughly 48 mph. Driving at 75 mph increases aerodynamic drag exponentially. Because the Sport Utility Vehicle - 4WD has a large frontal area, expect your real-world highway fuel economy to drop by up to 25% at high speeds.

5-Year Total Cost of Ownership

Estimated Monthly Cost
$800/mo
Includes estimated depreciation, fuel, insurance, and state fees over 5 years. Does not include loan interest.
15,000 mi
Value Depreciation
Est. value lost over 60 months
$20,580
42.9%
Fuel & Electricity
Based on National Average rates ($3.50/gal)
$15,441
32.2%
Estimated Insurance
Based on vehicle class risk profile
$11,575
24.1%
State Registration Fees
Based on National Average DMV base rates
$400
0.8%
Total 5-Year Cost$47,996

Recall Intelligence

Campaign #24V298000·2024-05-24
⛔ PARK IT
Component: SERVICE BRAKES, HYDRAULIC:POWER ASSIST:VACUUM

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2006-2012 ML, GL, and R-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. Moisture may accumulate and cause corrosion in the brake booster housing unit, which can result in reduced brake performance or brake failure.

Consequence & Remedy

Consequence: Reduced brake performance or brake failure can increase the risk of a crash.

Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will remove the rubber sleeve, inspect the brake booster, and as necessary, replace the brake booster. All repairs will be performed free of charge. Owner notification letters were mailed on May 24, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MMUSA's number for this recall is 2024050001/2. This recall is an expansion of previous recall number 22V-315.

Campaign #22V315000·2022-06-30
⛔ PARK IT
Component: SERVICE BRAKES, HYDRAULIC:POWER ASSIST:VACUUM

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2006-2012 ML-Class, GL-Class, and R-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. Moisture may accumulate and cause corrosion in the brake booster housing unit, which can result in reduced brake performance or brake failure.

Consequence & Remedy

Consequence: Reduced brake performance or brake failure can increase the risk of a crash.

Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will remove the rubber sleeve, inspect the brake booster, and as necessary, replace the brake booster. All repairs will be performed free of charge. Owner notification letters were mailed June 30, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers for this recall are 2022050014, 2022050015 2022090006, & 2022090007.

Campaign #16V081000·2016-10-18
critical
Component: AIR BAGS:FRONTAL:DRIVER SIDE:INFLATOR MODULE

Mercedes-Benz USA, LLC. (MBUSA) is recalling certain model year 2009-2010 ML320 BlueTec 4Matic, GL320 BlueTec 4Matic and R320 CDI 4Matic, 2011 E350 Cabriolet and E550 Cabriolet, 2009-2011 ML350, ML350 4Matic, ML550 4Matic, ML63 AMG, and C63 AMG, 2010-2011 ML450 4Matic Hybrid, E350 Coupe, E350 4Matic, E550 Coupe, E550 4Matic, and E63 AMG, 2011-2012 GL350 BlueTec 4Matic and R350 BlueTec 4Matic, 2009-2012 GL450 4Matic, GL550 4Matic and R350 4Matic, 2007-2008 SLK280, SLK350, and SLK55 AMG, 2011-2014 SLS AMG Coupe, 2012 SLS AMG Cabriolet, 2013-2014 SLS AMG GT and SLS AMG GT Cabriolet, 2005 C230 Kompressor and C320, 2006-2007 C230, 2006-2011 C350, 2008-2011 C300 and C300 4Matic, 2010-2012 GLK350 and GLK350 4Matic and 2007-2008 Chrysler Crossfire vehicles. Upon deployment of the driver's frontal air bag, excessive internal pressure may cause the inflator to rupture.

Consequence & Remedy

Consequence: In the event of a crash necessitating deployment of the driver's frontal air bag, the inflator could rupture with metal fragments striking the driver or other occupants resulting in serious injury or death.

Remedy: MBUSA will their notify owners, and Fiat Chrysler will notify the affected Chrysler owners. Dealers for the respective brands will replace the driver's frontal air bag module, free of charge. This recall began November 2016. Mercedes-Benz owners may contact MBUSA customer service at 1-800-367-6372 and Chrysler owners may contact Fiat Chrysler customer service at 1-800-853-1403.

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Looking for comprehensive historical data?

NHTSA FARS (Fatal Crash History) and broader generational safety trends are aggregated at the model level rather than by specific engine configurations. View the complete historical data profile for all Mercedes-Benz ML350 4matic configurations.

View Model History

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Fuel Cost Analysis

Annual Fuel Cost$4,050
vs. Avg Vehicle (5 yrs)Save $9,500

Based on 15,000 miles/year and current fuel prices.

Efficiency Breakdown

City15 MPG
Highway20 MPG
Combined17 MPG

Estimated Lifetime Carbon Footprint

(Based on 200,000 miles driven)

104.6 metric tons CO₂
Equivalent To:
🌳 129 tree seedlings grown for 10 yrs
✈️ 8.7 cross-country flights/yr

Data Provenance

Data directly from the EPA National Vehicle and Fuel Emissions Laboratory. The combined rating is a weighted average (55% city, 45% highway). For official figures, visit fueleconomy.gov.