43/100
2021Midsize CarsPremium

2021 Mercedes-Benz AMG E53 4matic Plus

EPA ID: 43360
22
City MPG
25
Combined MPG
25MPG· Average
29
Highway MPG

Fuel Economy Overview

The 2021 Mercedes-Benz AMG E53 4matic Plus achieves an EPA-estimated 25 MPG in combined city and highway driving, with 22 MPG in the city and 29 MPG on the highway. Powered by a 3L 6-cylinder engine paired with a automatic 9-spd, this midsize cars features 4-Wheel Drive drive.

In terms of environmental impact, the 2021 AMG E53 4matic Plus produces approximately 361 grams of CO2 per mile. This figure is measured under standardized EPA test conditions and represents tailpipe emissions only. For context, the average new vehicle sold in the United States produces approximately 400 grams of CO2 per mile, meaning this AMG E53 4matic Plus performs better than the national average in this regard.

The estimated annual fuel cost for this vehicle is $2,750, based on 15,000 miles of driving per year and current national average fuel prices. Compared to the average new vehicle, you would save $3,000 over a 5-year period. This calculation accounts for differences in fuel consumption efficiency and provides a practical measure of long-term ownership costs attributable to fuel economy.

Energy DNA

Vehicle ClassMidsize Cars
Fuel TypePremium
Engine3L 6-cyl
AspirationNaturally Aspirated
TransmissionAutomatic 9-spd
Drive Type4-Wheel Drive

Green Scorecard

CO2 Emissions361 g/mi
Start-Stop SystemEquipped
GHG Score5/10
Smog RatingN/A
Est. Annual Cost$2,750
5-Year Cost DeltaSave $3,000

Personalized Commute CalculatorEPA defaults to 55% City / 45% Hwy

55% City45% Highway

Adjust the slider to match your daily driving habits. City driving involves stop-and-go traffic under 45mph, while highway driving represents sustained speeds over 55mph.

Your Real MPG
24.7
Impact vs EPA
+$27
/ year
💨

Aerodynamic Speed Penalty

EPA highway tests average roughly 48 mph. Driving at 75 mph increases aerodynamic drag exponentially. Expect your real-world highway fuel economy to drop by roughly 15-20% at interstate speeds.

5-Year Total Cost of Ownership

Estimated Monthly Cost
$736/mo
Includes estimated depreciation, fuel, insurance, and state fees over 5 years. Does not include loan interest.
15,000 mi
Value Depreciation
Est. value lost over 60 months
$22,400
50.7%
Fuel & Electricity
Based on National Average rates ($3.50/gal)
$10,500
23.8%
Estimated Insurance
Based on vehicle class risk profile
$10,840
24.6%
State Registration Fees
Based on National Average DMV base rates
$400
0.9%
Total 5-Year Cost$44,140

Recall Intelligence

Campaign #24V445000·2024-11-15
critical
Component: ELECTRICAL SYSTEM:WIRING

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLS 53 4MATIC, 2019-2023 E 53 4MATIC Cabriolet, E 53 4MATIC Coupe, E 53 4MATIC Sedan, 2021-2024 GT 43 4MATIC, and 2019-2025 GT 53 4MATIC vehicles. The transmission wiring harness connection might not have been correctly wired during a prior recall repair, and during production. which can expose the electrical connector to corrosion, and result in an electrical short-circuit.

Consequence & Remedy

Consequence: An electrical short circuit can increase the risk of a fire.

Remedy: Dealers will replace the two-part wiring harness and connector, free of charge. Interim letters, notifying owners of the safety risk, were mailed August 9, 2024. A second notice will be sent once the final remedy is available. Owners may contact MBUSA customer service at 1-877-496-3691. MBUSA's number for this recall is 2024100002/3. This recall supersedes recall 22V-533. Vehicles repaired under the prior recall will still need to have the new remedy performed.

Campaign #24V100000·2024-03-22
critical
Component: ELECTRICAL SYSTEM:WIRING

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 CLS450, E450, E450 All-Terrain, AMG E53, AMG GT43, AMG GT53, and 2021 AMG CLS53 vehicles. The 48-volt ground cable connection located in the engine compartment may not be tightened properly and may result in the ground cable overheating.

Consequence & Remedy

Consequence: An overheated ground cable increases the risk of a fire.

Remedy: Dealers will inspect the 48-volt ground cable connection and repair it as necessary, free of charge. Owner notification letters were mailed March 22, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024MMNNNN.

Campaign #23V880000·2024-02-23
critical
Component: FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.

Consequence & Remedy

Consequence: A loss of drive power can increase the risk of a crash.

Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 28, 2024. Owner notification letters will be mailed in phases, on February 23, 2024, April 19, 2024, June 28, 2024, August 9, 2024, October 1, 2024, and December 2, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of NHTSA recall number 23V-445.

Campaign #22V733000·2023-01-20
critical
Component: ELECTRICAL SYSTEM:12V/24V/48V BATTERY

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2022 CLS450 Coupe and AMG E53, 2019-2021 AMG CLS53 Coupe, and 2021-2022 E450 vehicles. The 12-Volt battery in the trunk may not be properly secured, which, in the event of a crash, can cause electrical connection failure, disabling various safety features including, emergency call (eCall) system, electric seat adjustment, hazard warning lights, and automatic door locks.

Consequence & Remedy

Consequence: The inability to operate safety features (eCall system, hazard lights, electric seats, or automatic door locks) can increase the risk of injury during a crash.

Remedy: Dealers will secure the 12V battery, free of charge. Owner notification letters were mailed January 20, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022100009.

Campaign #22V533000·2022-10-14
critical
Component: ELECTRICAL SYSTEM:WIRING

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 AMG GT43, 2019-2022 AMG E53, E53 Coupe, E53 Cabriolet, AMG GT53, and 2019-2021 AMG CLS53 vehicles. The transmission wiring harness may be misrouted, which can expose the electrical connector to corrosion, and result in an electrical short-circuit.

Consequence & Remedy

Consequence: An electrical short-circuit can increase the risk of a fire.

Remedy: Dealers will inspect and repair the electrical connector, as necessary. Dealers will also reroute the harness and install an additional bracket. All repairs will be performed free of charge. Owner notification letters were mailed October 14, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022080010.

Campaign #22V365000·2022-07-08
moderate
Component: COMMUNICATION: AUTO CRASH NOTIFICATION

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.

Consequence & Remedy

Consequence: A disabled eCall system would prevent a vehicle occupant from contacting the emergency services call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.

Remedy: The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers are for this recall is 2022060005 and 2023110006.

Campaign #22V189000·2022-05-09
critical
Component: STEERING: STEERING WHEEL/HANDLE BAR

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.

Consequence & Remedy

Consequence: Deactivated hands-off detection will prevent DISTRONIC system features from functioning, including warnings to grab the steering wheel and calling first responders as part of the Active Emergency Stop Assist, which can increase the risk of a crash or injury.

Remedy: Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.

Campaign #21V483000·2021-09-24
critical
Component: SEAT BELTS:REAR/OTHER:RETRACTOR

Mercedes-Benz, LLC (MBUSA) is recalling certain 2021 G550, AMG G63, E350, E450, AMG CLS53, AMG E53, AMG GT43, AMG GT53, AMG GT63, 2021-2022 CLS450, and AMG E63 vehicles. The rear seat belt automatic locking retractors may deactivate early, which can prevent the child restraint system from securing properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 208, "Occupant Crash Protection."

Consequence & Remedy

Consequence: An unsecured child restraint system can increase the risk of injury during a crash.

Remedy: Dealers will inspect, and replace as necessary, the rear seat belt assemblies, free of charge. Owners notified of the voluntary recall campaign by an interim letter on August 13, 2021. A final letter was mailed on September 24, 2021. Owners may contact MBUSA customer service at 1-800-367-6372.

Campaign #21V527000·2021-09-03
critical
Component: AIR BAGS:SENSOR:SIDE IMPACT

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 CLS450, AMG E53, AMG CLS53, E350, E450, AMG GT43, AMG GT53, 2020 S450, S560, G550, AMG GLC63, 2020-2021 GLC300, and AMG G63 vehicles. The side crash sensor connectors may come loose, which could delay the activation of air bags and seatbelts during a side impact crash.

Consequence & Remedy

Consequence: Air bags and seatbelts that don't function as intended can increase the risk of injury during a crash.

Remedy: Dealers will inspect and replace as necessary, the side impact crash sensors, free of charge. Owner notification letters were mailed on September 3, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021070032/33.

Campaign #21V406000·2021-07-16
critical
Component: SEATS:MID/REAR ASSEMBLY:HEAD RESTRAINT

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 C300 Cabriolet, C43 AMG Cabriolet, C63 AMG Cabriolet, C63 AMG S Cabriolet, E450 Cabriolet, and E53 AMG Cabriolet vehicles. The rear headrests may be incorrectly mounted to the seatbacks.

Consequence & Remedy

Consequence: Incorrectly mounted headrests could move or detach from the seat during a crash, increasing the risk of injury.

Remedy: Dealers will inspect the rear seatback guide bushings and replace them if necessary, free of charge. Owner notification letters were mailed July 16, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021060010.

Campaign #21V354000·2021-06-28
critical
Component: BACK OVER PREVENTION: SENSING SYSTEM: CAMERA

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The MBUX multimedia system software may cause the display to remain black, or reboot after startup. This could result in the rearview camera image not displaying properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 111, "Rear Visibility."

Consequence & Remedy

Consequence: A backup camera that displays a blank image reduces the driver's rear view, increasing the risk of a crash or injury.

Remedy: The multimedia system software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed beginning June 28, 2021. Owners may contact MBUSA customer service at 1-800-367-6373. MBUSA's number for this recall is 2021050012.

Campaign #21V230000·2021-05-21
critical
Component: SEAT BELTS:PRETENSIONER

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 C-Class, E-Class, E-Class Coupe and Convertible, GLC, CLS, AMG GT 4-door Coupe and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. A faulty electrical contact within the seat position switch may prevent the driver and passenger air bags and seat belt force limiters from properly activating during a crash.

Consequence & Remedy

Consequence: Air bags and seat belts that do not perform properly in a crash can increase the risk of injury.

Remedy: MBUSA will notify owners, and dealers will replace the seat position switches, free of charge. Owner letters were mailed May 21, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021040016.

Campaign #21V216000·2021-04-29
critical
Component: SEATS:FRONT ASSEMBLY:POWER ADJUST

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, E63S AMG, 2020 E63S AMG Wagon, and 2020-2021 E53 AMG vehicles. The passenger seat limiter may allow the seat to be positioned too close to the air bag.

Consequence & Remedy

Consequence: A seat too close to the air bag increases the risk of injury in the event of a crash necessitating the deployment of the frontal passenger air bag.

Remedy: MBUSA will notify owners, and dealers will recalibrate the passenger seat limiter, free of charge. The recall began April 29, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021040002.

Campaign #21V058000·2021-03-12
critical
Component: COMMUNICATION: AUTO CRASH NOTIFICATION

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the emergency call system (eCall) in the event of a crash.

Consequence & Remedy

Consequence: Failure of the eCall system may result in emergency responders being dispatched to the wrong location, increasing the risk of injury following a crash.

Remedy: MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267. MBUSA's number for this recall is 2021020025.

Campaign #20V673000·2020-12-18
critical
Component: SEATS

Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 E350 and E450, 2019-2021 AMG E53 and 2020-2021 AMG E63 vehicles. The front passenger seat may be missing the mechanical seat adjustment range limit stop, allowing the seat to move outside of the acceptable range in relation to the air bag.

Consequence & Remedy

Consequence: If the front passenger seat is adjusted beyond the acceptable range in relation to the air bag, there could be an increased risk of injury in the event of a crash with air bag deployment.

Remedy: MBUSA will notify owners, and dealers will inspect for the mechanical seat adjustment range limitation for the front passenger seat and install it if necessary, free of charge. The recall began December 18, 2020. Owners may contact MBUSA customer service at 1-800-368-6372. MBUSA's number for this recall is 2020110013.

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Looking for comprehensive historical data?

NHTSA FARS (Fatal Crash History) and broader generational safety trends are aggregated at the model level rather than by specific engine configurations. View the complete historical data profile for all Mercedes-Benz AMG E53 4matic Plus configurations.

View Model History

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Fuel Cost Analysis

Annual Fuel Cost$2,750
vs. Avg Vehicle (5 yrs)Save $3,000

Based on 15,000 miles/year and current fuel prices.

Efficiency Breakdown

City22 MPG
Highway29 MPG
Combined25 MPG

Estimated Lifetime Carbon Footprint

(Based on 200,000 miles driven)

72.2 metric tons CO₂
Equivalent To:
🌳 89 tree seedlings grown for 10 yrs
✈️ 6.0 cross-country flights/yr

Data Provenance

Data directly from the EPA National Vehicle and Fuel Emissions Laboratory. The combined rating is a weighted average (55% city, 45% highway). For official figures, visit fueleconomy.gov.