2021 Toyota Sienna Hybrid AWD
Fuel Economy Overview
The 2021 Toyota Sienna Hybrid AWD achieves an EPA-estimated 35 MPG in combined city and highway driving, with 35 MPG in the city and 36 MPG on the highway. Powered by a 2.5L 4-cylinder engine paired with a automatic (av-s6), this minivan - 4wd features All-Wheel Drive drive.
In terms of environmental impact, the 2021 Sienna Hybrid AWD produces approximately 253 grams of CO2 per mile. This figure is measured under standardized EPA test conditions and represents tailpipe emissions only. For context, the average new vehicle sold in the United States produces approximately 400 grams of CO2 per mile, meaning this Sienna Hybrid AWD performs better than the national average in this regard.
The estimated annual fuel cost for this vehicle is $1,700, based on 15,000 miles of driving per year and current national average fuel prices. Compared to the average new vehicle, you would spend $2,250 over a 5-year period. This calculation accounts for differences in fuel consumption efficiency and provides a practical measure of long-term ownership costs attributable to fuel economy.
Energy DNA
Green Scorecard
Personalized Commute CalculatorEPA defaults to 55% City / 45% Hwy
Adjust the slider to match your daily driving habits. City driving involves stop-and-go traffic under 45mph, while highway driving represents sustained speeds over 55mph.
The Brick Effect: Highway Speed Penalty
EPA highway tests average roughly 48 mph. Driving at 75 mph increases aerodynamic drag exponentially. Because the Minivan - 4WD has a large frontal area, expect your real-world highway fuel economy to drop by up to 25% at high speeds.
5-Year Total Cost of Ownership
Recall Intelligence
Toyota Motor Engineering & Manufacturing (Toyota) is recalling certain 2021-2025 Sienna Hybrid vehicles. The bolts for the seatbacks on the third-row seat assemblies may not be tightened properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) numbers 202, "Head Restraints," 207, "Seating Systems," and 225, "Child Restraint Anchorage Systems."
Consequence & Remedy
Consequence: An improperly tightened seatback may not adequately restrain the occupant during a crash, increasing their risk of injury.
Remedy: Dealers will tighten the seat assembly bolts, free of charge. Owner notification letters were mailed April 1, 2025. Owners may contact Toyota's customer service at 1-800-331-4331. Toyota's number for this recall is 25TA05.
Toyota Motor Engineering & Manufacturing (Toyota) is recalling certain 2020-2021 Avalon, Avalon Hybrid, Corolla, Highlander, Highlander Hybrid, RAV4, RAV4 Hybrid, Lexus ES350, Lexus RX350, Lexus RX450H, 2021 Sienna Hybrid, Lexus ES250, 2020-2022 Camry, Camry Hybrid, and ES300H vehicles. A short circuit may develop in the Occupant Classification System (OCS) sensor, preventing the front passenger air bag from deploying.
Consequence & Remedy
Consequence: An air bag that does not deploy during a crash increases the risk of injury.
Remedy: Dealers will inspect and replace the sensor as necessary, free of charge. Interim letters notifying owners of the safety risk were mailed in February 2024. Some final remedy owner letters were mailed October 31, 2024. Letters will continue to be mailed in phases through January 2026. Owners may contact Toyota customer service at 1-800-331-4331. Toyota's number for this recall is 23TB15/23TA15 Lexus 23LB03/23LA03.
Toyota Engineering & Manufacturing (Toyota) is recalling certain 2022 Lexus LX 600, Lexus NX 350h, Lexus NX 450h+, Toytoa RAV4 Hybrid, 2021-2022 Lexus LS 500h, Toyota Mirai, RAV4 PRIME, Sienna, Venza, and 2020-2022 Toyota Highlander Hybrid vehicles. The Skid Control ECU software may not turn on the Vehicle Stability Control (VSC) system when the vehicle is restarted after the driver has disabled the VSC system. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 126, "Electronic Stability Control Systems."
Consequence & Remedy
Consequence: Driving with a deactivated stability control system increases the risk of a crash.
Remedy: Dealers will update the Skid Control ECU software, free of charge. Owner notification letters were mailed May 27, 2022. Owners may contact Toyota customer service at 1-800-331-4331. Toyota's number for this recall is 22TA03. Lexus' number for this recall is 22LA01.
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Looking for comprehensive historical data?
NHTSA FARS (Fatal Crash History) and broader generational safety trends are aggregated at the model level rather than by specific engine configurations. View the complete historical data profile for all Toyota Sienna Hybrid AWD configurations.
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Fuel Cost Analysis
Based on 15,000 miles/year and current fuel prices.
Efficiency Breakdown
Estimated Lifetime Carbon Footprint
(Based on 200,000 miles driven)